Ivermectin is primarily known as an antiparasitic medication after its discovery in 1975,but has attracted interest for its potential role in cancer treatment.

Here's a breakdown of its potential connection to cancer:

1. Research Interest: Research has explored whether ivermectin can impact cancer cells and tumors. The studies are mostly in preclinical stages, meaning they are conducted in laboratories or animal models rather than in humans.

2. Mechanisms: Ivermectin is thought to have several potential anti-cancer mechanisms:

- Inhibition of Cancer Cell Growth: It may affect cellular signaling pathways that control cancer cell proliferation.

- Inducing Apoptosis: The drug may promote apoptosis, a process of programmed cell death, in cancer cells.

- Interference with Microenvironment: Ivermectin might alter the tumor microenvironment, making it less conducive to cancer growth and spread.

3. Types of Cancer Studied: Various types of cancer have been investigated in preclinical studies, including breast, colorectal, prostate, and glioblastoma. The effects observed vary depending on the type of cancer and the study design.

4. Clinical Trials: Currently, there is limited data from human clinical trials to conclude definitively about ivermectin’s effectiveness or safety in cancer therapy. Some trials are in progress, but more extensive clinical research is needed.

5. Combination Therapies: Researchers are also looking at how ivermectin might work with conventional cancer therapies, such as chemotherapy, to enhance effectiveness or reduce resistance to treatment.

6. Safety and Regulation: As of now, ivermectin is not approved for cancer treatment by any major health regulatory agencies. Any use for cancer treatment should be under strict clinical settings and with professional oversight.

Overall, while the early findings are intriguing, it’s important for ongoing and future research to validate these potential uses. If you're interested in the latest developments regarding ivermectin and cancer, it's a good idea to stay updated on clinical trials and research publications in this field. Always consult with healthcare professionals before considering experimental treatments.

Educate yourself more with this peer reviewed article:

https://pmc.ncbi.nlm.nih.gov/articles/PMC3043740/